Jaafar Bennouna Selected Research

ProLindac

9/2007

Phase I and pharmacokinetic trial of AP5346, a DACH-platinum-polymer conjugate, administered weekly for three out of every 4 weeks to advanced solid tumor patients.

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Jaafar Bennouna Research Topics

Disease

54	Neoplasms (Cancer) 04/2022 - 01/2002
37	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 04/2002
35	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2022 - 03/2008
19	Disease Progression 01/2022 - 05/2010
11	Adenocarcinoma 12/2020 - 05/2009
8	Asthenia 01/2021 - 09/2011
8	Neutropenia 01/2021 - 05/2010
8	Fatigue 04/2018 - 05/2010
7	Colonic Neoplasms (Colon Cancer) 01/2022 - 05/2016
7	Lung Neoplasms (Lung Cancer) 11/2021 - 03/2012
6	Pancreatic Neoplasms (Pancreatic Cancer) 01/2017 - 05/2009
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2022 - 08/2017
5	Carcinoma (Carcinomatosis) 04/2021 - 09/2005
5	Exanthema (Rash) 12/2018 - 09/2012
5	Stomatitis 12/2018 - 10/2012
4	Diarrhea 01/2022 - 05/2010
4	Esophageal Neoplasms (Esophageal Cancer) 07/2021 - 04/2019
4	Malignant Mesothelioma 01/2020 - 01/2019
4	Hypertension (High Blood Pressure) 01/2020 - 03/2011
4	Breast Neoplasms (Breast Cancer) 12/2019 - 03/2008
4	Vomiting 12/2018 - 09/2007
4	Febrile Neutropenia 12/2018 - 05/2010
4	Nausea 09/2013 - 09/2007
4	Abdominal Pain (Pain, Abdominal) 10/2011 - 05/2010
3	Neoplasm Metastasis (Metastasis) 01/2020 - 09/2005
3	Renal Cell Carcinoma (Grawitz Tumor) 01/2020 - 11/2008
3	Thrombocytopenia (Thrombopenia) 12/2018 - 05/2010
3	Adenocarcinoma of Lung 01/2017 - 09/2013
2	Biliary Tract Neoplasms (Biliary Tract Cancer) 01/2021 - 11/2014
2	Microsatellite Instability 12/2020 - 11/2020
2	Pain (Aches) 04/2020 - 09/2013
2	Edema (Dropsy) 01/2020 - 05/2010
2	Melanoma (Melanoma, Malignant) 01/2020 - 01/2002
2	Mesothelioma 01/2020 - 01/2019
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2017 - 04/2015
2	Acne Vulgaris 02/2015 - 09/2013
2	Constipation 06/2012 - 05/2010
2	Hand-Foot Syndrome 10/2011 - 01/2009
2	Prostatic Neoplasms (Prostate Cancer) 02/2006 - 09/2003
1	Insulinoma 01/2022
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2022

Drug/Important Bio-Agent (IBA)

16	Bevacizumab (Avastin)FDA Link 01/2022 - 05/2009
15	Fluorouracil (Carac)FDA LinkGeneric 01/2022 - 01/2007
14	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2022 - 05/2008
14	PlatinumIBA 01/2020 - 09/2007
12	Docetaxel (Taxotere)FDA Link 01/2022 - 05/2010
12	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 09/2011
11	pembrolizumabIBA 07/2022 - 01/2018
11	Irinotecan (Camptosar)FDA LinkGeneric 12/2020 - 04/2002
10	Leucovorin (Folinic Acid)FDA Link 01/2020 - 04/2002
9	AfatinibIBA 01/2022 - 09/2013
8	Tyrosine Kinase InhibitorsIBA 01/2020 - 06/2014
8	Gemcitabine FDA Link 12/2018 - 05/2009
6	ErbB Receptors (EGF Receptor)IBA 01/2022 - 06/2014
5	Cetuximab (Erbitux)FDA Link 01/2022 - 05/2012
5	Biomarkers (Surrogate Marker)IBA 10/2021 - 01/2017
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 03/2011
5	Pemetrexed (MTA)FDA Link 01/2019 - 09/2013
5	Pharmaceutical PreparationsIBA 12/2018 - 06/2012
5	vinflunineIBA 06/2012 - 10/2005
4	Immune Checkpoint InhibitorsIBA 11/2021 - 01/2020
4	AntibodiesIBA 10/2021 - 01/2002
4	B7-H1 AntigenIBA 07/2021 - 01/2019
4	Proteins (Proteins, Gene)FDA Link 04/2021 - 01/2002
4	130-nm albumin-bound paclitaxelIBA 04/2020 - 01/2017
3	avelumabIBA 04/2022 - 01/2019
3	Protons (Proton)IBA 08/2021 - 08/2019
3	folfirinoxIBA 01/2019 - 05/2011
3	Capecitabine (Xeloda)FDA Link 01/2018 - 02/2011
3	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2017 - 05/2009
3	Vinorelbine (Navelbine)FDA LinkGeneric 01/2016 - 10/2011
2	Biological ProductsIBA 01/2022 - 11/2021
2	NivolumabIBA 01/2021 - 11/2020
2	IpilimumabIBA 01/2021 - 11/2020
2	Interferon Type IIBA 01/2021 - 01/2020
2	Paclitaxel (Taxol)FDA LinkGeneric 12/2020 - 09/2011
2	durvalumabIBA 04/2020 - 01/2020
2	Axitinib (AG 013736)IBA 01/2020 - 03/2011
2	chemotactic factor inactivatorIBA 01/2020 - 01/2018
2	LigandsIBA 01/2019 - 10/2005
2	Neoplasm Antigens (Tumor Antigens)IBA 11/2018 - 03/2012
2	nintedanibIBA 01/2017 - 11/2015
2	AntigensIBA 01/2017 - 03/2002
2	XELOXIBA 02/2011 - 05/2008
2	Interleukin-2 (IL2)IBA 10/2010 - 11/2008
2	CeramidesIBA 02/2006 - 09/2003
2	AndrogensIBA 02/2006 - 09/2003
2	Peptides (Polypeptides)IBA 03/2002 - 01/2002
1	Serum AlbuminIBA 04/2022
1	pertuzumabIBA 01/2022

Therapy/Procedure

44	Drug Therapy (Chemotherapy) 01/2022 - 04/2002
23	Therapeutics 01/2022 - 09/2003
5	Adjuvant Chemotherapy 01/2019 - 04/2002
4	Immunotherapy 01/2020 - 10/2005
3	Proton Therapy 08/2021 - 08/2019
3	Radiotherapy 11/2014 - 09/2011
2	Duration of Therapy 10/2021 - 01/2018
2	Precision Medicine 10/2021 - 01/2020
2	Chemoradiotherapy 04/2021 - 11/2014
2	Induction Chemotherapy 01/2020 - 01/2018